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Oral bioavailability of naproxen-β-cyclodextrin inclusion compound

✍ Scribed by F.J. Otero-Espinar; S. Anguiano-Igea; N. García-Gonzalez; J.L. Vila-Jato; J. Blanco-Méndez

Book ID
113365459
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
644 KB
Volume
75
Category
Article
ISSN
0378-5173

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Studies of the Naproxen:β-Cyclodextrin I
Studies of the Naproxen:β-Cyclodextrin Inclusion Complex
✍ J. Wang; I.M. Warner 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 413 KB

The interaction of a nonsteroidal anti-inflammatory drug, naproxen, with \(\beta\)-CD has been studied by several analytical techniques, including 1-D and 2-D proton NMR, fluorescence spectroscopy, and FAB-MS. The negative ion FAB-MS confirmed the existence of a 1:1 inclusion complex of naproxen and