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Oral administration of a streptococcal agent OK-432 activates peritoneal macrophages in mice

✍ Scribed by Iwao Suzuki; Akira Kinoshita; Hideki Tanaka; Toshiro Yadomae

Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 614 KB
Volume: 13
Category: Article
ISSN: 0192-0561
DOI: 10.1016/0192-0561(91)90092-l

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Mouse spleen cells, either pretreated in vitrowith 100 U/ ml of OK-432-induced IFN gamma for 18 h or obtained from mice 24 or 48 h after i.v. injection of OK-432( 100 fig/ mouse), were examined for their anti-tumor effect by Winn's neutralization assay against Meth-A tumor cells in BALB/c mice. Sple