Oral absorption of anti-aids nucleoside analogues. 1. Intestinal transport of didanosine in rat and rabbit preparations

Oral absorption of anti- AIDS nucleoside

Oral absorption of anti- AIDS nucleoside analogues. 3. Regional absorption and in vivo permeability of 2′, 3′ - dideoxyinosine in an intestinal–vascular access port (IVAP) dog model

✍ Patrick J. Sinko; John P. Sutyak; Glen D. Leesman; Peidi Hu; Vijaya D. Makhey; H 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 389 KB

The absolute oral and regional intestinal bioavailabilities (BAs) and pharmacokinetics (PK) of 2 H , 3 H -dideoxyinosine (ddI), a nucleoside analog used in the treatment of human immunode®ciency virus (HIV) infection, were investigated in an in vivo intestinal± vascular access port (IVAP) dog model.