OR.57. Deficiency of miR-146 Contributes to Abnormal Activation of Type I Interferon Pathway in Systemic Lupus Erythematosus

MicroRNA-146a contributes to abnormal ac

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

✍ Yuanjia Tang; Xiaobing Luo; Huijuan Cui; Xuming Ni; Min Yuan; Yanzhi Guo; Xinfan 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 294 KB

## Abstract ## Objective MicroRNA have recently been identified as regulators that modulate target gene expression and are involved in shaping the immune response. This study was undertaken to investigate the contribution of microRNA‐146a (miR‐146a), which was identified in the pilot expression pr