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OR13,77 Insulin-like growth factors (IGFs) and IGF binding proteins in PSA-detected prostate cancer: a population-based case control study

✍ Scribed by M.-A. Rowlands; J.M.P. Holly; D. Gunnell; J. Donovan; J. Lane; F. Hamdy; D. Neal; R.M. Martin

Book ID: 117734859
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 65 KB
Volume: 20
Category: Article
ISSN: 1096-6374
DOI: 10.1016/s1096-6374(10)70093-9

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Insulin-like growth factor-I (IGF-I) has mitogenic and anti-apoptotic properties and has been implicated in the development of breast, colorectum, prostate and lung cancer. IGF binding proteins (IGFBPs) are not only carrier proteins for IGFs but also hold a central position in IGF ligand-receptor in