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Optofluidic stretching of RBCs using single optical tweezers

โœ Scribed by S. K. Mohanty; A. Uppal; P. K. Gupta

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
315 KB
Volume
1
Category
Article
ISSN
1864-063X

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โœฆ Synopsis

Abstract

Our previous studies demonstrated a huge difference in rotational speed of trapped red blood cells under diseased condition, which was presumably attributed to change in viscoelastic properties. Here, we report use of single optical tweezers combined with viscous drag for stretching of the trapped cell. Significant differences were observed in the measured viscoelastic parameters of fresh and aged/malariaโ€infected RBCs under hypotonic condition. The technique was also found to provide information about adhesion properties of RBCs. (ยฉ 2008 WILEYโ€VCH Verlag GmbH & Co. KGaA, Weinheim)

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