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Options of genetic testing and methylation analysis of circulating free tumor DNA (tumor cell-free DNA) isolated from peripheral blood of NSCLC patients

✍ Scribed by Pešek, Miloš; Benešová, Lucie; Kopečková, Marta; Belšánová, Barbora; Fiala, Ondřej; Minárik, Marek

Book ID
119320858
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
53 KB
Volume
77
Category
Article
ISSN
0169-5002

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## Abstract Abnormal DNA methylation is a feature of most types of cancer, which is reflected in cell‐free circulating DNA in plasma. It is, however, unknown whether surgical removal of the tumor and subsequent therapy induces changes in plasma DNA methylation, which can be used to monitor treatmen