Optimizing treatment for elderly patients with acute promyelocytic leukemia: is it time to replace chemotherapy with all-trans retinoic acid and arsenic trioxide?
β Scribed by Tsimberidou, Apostolia-Maria; Kantarjian, Hagop; Keating, Michael J.; Estey, Elihu
- Book ID
- 121268127
- Publisher
- Informa plc
- Year
- 2006
- Tongue
- English
- Weight
- 421 KB
- Volume
- 47
- Category
- Article
- ISSN
- 1042-8194
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π SIMILAR VOLUMES
This study was conducted to compare the results of treatment of acute promyelocytic leukemia (APL) with all-trans retinoic acid alone (ATRA) or a combination therapy of ATRA followed by chemotherapy. Forty-three patients treated between February 1992 and February 1996 were included in this study. Ei
## Abstract The use of arsenic trioxide (As~2~O~3~, ATO) combined with allβtrans retinoic acid (ATRA) has recently been reported to induce remission in patients with acute promyelocytic leukemia (APL). However, its efficiency remains inconclusive mainly due to the small number of the available case