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Optimizing the Substrate Specificity of a Group I Intron Ribozyme †

✍ Scribed by Zarrinkar, Patrick P.; Sullenger, Bruce A.

Book ID
126417263
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
88 KB
Volume
38
Category
Article
ISSN
0006-2960

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The mitochondrial DNA molecules of two interfertile algal species, Chlamydomonas smithii and C. reinhardtii, are co-linear except for a 1075 bp intron (the e-insert) that is present in the cob gene of C. smithii. The e-insert, a group I intron (Cs cob" 1) containing an open reading frame (ORF) which