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Optimizing adenoviral transfection of mesenchymal stem cells is necessary for accelerated osteogenesis and angiogenesis

✍ Scribed by Marc A. Soares; Björn H. Schönmeyr; John G. Fernandez; Nicholas W. Clavin; Babak J. Mehrara

Book ID
113678723
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
46 KB
Volume
207
Category
Article
ISSN
1072-7515

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## Abstract Human mesenchymal stem cell (hMSC) differentiation into osteoblasts and the signaling events involved are poorly understood. We recently established that contact with specific extracellular matrix (ECM) proteins, in particular laminin‐5, is sufficient to induce an osteogenic phenotype i