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Optimized THP-1 differentiation is required for the detection of responses to weak stimuli

✍ Scribed by E. K. Park; H. S. Jung; H. I. Yang; M. C. Yoo; C. Kim; K. S. Kim


Book ID
105752964
Publisher
SP Birkhäuser Verlag Basel
Year
2007
Tongue
English
Weight
509 KB
Volume
56
Category
Article
ISSN
1420-908X

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## Abstract Many mammalian SWI/SNF complexes use Brahma‐related gene 1 (Brg1) as a catalytic subunit to remodel nucleosomes for transcription regulation. In several mesenchymal cells and tissues, expression of a defective Brg1 protein negates the normal activity of the SWI/SNF complex and delays or