## Abstract Salicylate‐based poly(anhydride‐esters), collectively referred to as PolyAspirin™, hydrolytically degrade into salicylic acid, a nonsteroidal anti‐inflammatory drug (NSAID). The variations of the poly(anhydride‐ester) investigated in this article are linked by adipic acid, suberic acid,
Optimized Synthesis of Salicylate-based Poly( anhydride-esters)
✍ Scribed by Robert C. Schmeltzer; Theodore J. Anastasiou; Kathryn E. Uhrich
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 613 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0170-0839
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📜 SIMILAR VOLUMES
## Abstract A polymer blend consisting of antimicrobials (chlorhexidine, clindamycin, and minocycline) physically admixed at 10% by weight into a salicylic acid‐based poly (anhydride‐ester) (SA‐based PAE) was developed as an adjunct treatment for periodontal disease. The SA‐based PAE/antimicrobial
## Abstract **Summary:** Poly(ester‐anhydrides) were synthesised from poly(L‐lactide), poly(D,L‐lactide), and poly(__ε__‐caprolactone) prepolymers prepared by ring‐opening polymerisation of cyclic esters in the presence of 1,4‐butanediol or ricinoleic acid as co‐initiator. The hydroxyl group end fu
## Abstract The objective of this study was to prepare high molecular weight poly(ester‐anhydride)s by melt polycondensation. The polymerization procedure consisted of the preparation of carboxylic acid terminated poly(ϵ‐caprolactone) prepolymers that were melt polymerized to poly(ϵ‐caprolactone)s
## Abstract Fast‐degrading, salicylate‐based poly(anhydride‐esters) were designed to degrade and release the active component, salicylic acid (SA), within 1 week. The polymer degradation was enhanced by using shorter or oxygen‐containing aliphatic chains. A copolymer of diglycolic acid was also mad