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Optimized production of 2,3-butanediol by a lactate dehydrogenase-deficient mutant ofKlebsiella pneumoniae

✍ Scribed by Lee, Sung-Mok; Oh, Baek-Rock; Park, Jang Min; Yu, Anna; Heo, Sun-Yeon; Hong, Won-Kyung; Seo, Jeong-Woo; Kim, Chul Ho

Book ID: 121581559
Publisher: The Korean Society for Biotechnology and Bioengineering
Year: 2013
Tongue: English
Weight: 307 KB
Volume: 18
Category: Article
ISSN: 1226-8372
DOI: 10.1007/s12257-013-0396-z

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## Abstract __Klebsiella pneumoniae__ HR526, a new isolated 1,3‐propanediol (1,3‐PD) producer, exhibited great productivity. However, the accumulation of lactate in the late‐exponential phase remained an obstacle of 1,3‐PD industrial scale production. Hereby, mutants lacking D‐lactate pathway were