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Optimized, highly efficient transfer of foreign genes into newborn mouse hearts in vivo

✍ Scribed by Henning Ebelt; Thomas Braun


Book ID
116287193
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
325 KB
Volume
310
Category
Article
ISSN
0006-291X

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Mouse genetic manipulation has provided an excellent system to characterize gene function in numerous contexts. A number of mutants have been produced by using transgenic, gene knockout, and mutagenesis techniques. Nevertheless, one limitation is that it is difficult to express a gene in vivo in a r