✦ LIBER ✦

Optimized detection of small spin–spin couplings in two-dimensional chemical shift correlation experimentsCOSY and DEPT

✍ Scribed by Gy. Batta; Katalin E. Kövér

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 350 KB
Volume: 25
Category: Article
ISSN: 0749-1581
DOI: 10.1002/mrc.1260250208

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✦ Synopsis

Two-dimensional chemical shift correlation experiments (COSY and DEPT

) may be applied to the detection of small spin-spin couplings. To increase the sensitivity of these techniques, careful optimization of the experimental parameters is required. Equations applicable to AX spin systems are given for the optimal choice of delay periods in the pulse sequences. Practical applications have been demonstrated for oligosaccharide sequencing.

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