𝔖 Bobbio Scriptorium
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Optimization of wet granulation of a dothiepin HCl formulation

✍ Scribed by G. R. Sadeghnejad; A. R. Rajabi-Siahboomi

Book ID
118111025
Publisher
Pharmaceutical Press
Year
1998
Tongue
English
Weight
102 KB
Volume
50
Category
Article
ISSN
2042-7158

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Aplaviroc 200 mg tablets were made by a high shear wet granulation process. A formulation and process DOE were carried out to define formulation and process parameters at pilot scale in GSKs R&D facility. During the scale up, several batches made at the production facility dissolved slower than the