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Optimization of short hairpin RNA for lentiviral-mediated RNAi against WAS

✍ Scribed by Laurence Jeanson-Leh; Johanna Blondeau; Anne Galy

Book ID: 116295501
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 198 KB
Volume: 362
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2007.08.013

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## Abstract ## Background Although human islet transplantation is a promising approach for treating type I diabetes, its success is limited as a result of the poor survival rate of transplanted islets. Expression of a growth factor gene to promote revascularization and silencing of pro‐apoptotic g