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Optimization of operating temperature for continuous glucose isomerase reactor system

✍ Scribed by Sun Ho Park; Sun Bok Lee; Dewey D. Y. Ryu

Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
727 KB
Volume
23
Category
Article
ISSN
0006-3592

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✦ Synopsis

Abstract

The Optimal temperature control policy for an immobilized glucose isomerase reactor system was studied. This optimization study takes into consideration the enzyme deactivation during the continuous reactor operation. The Kinetic parameters including reduced Michaelis–Menten constant (K̄~m~), reduced maximum reaction rate (V̄~m~), equilibrium constant (K~e~), and enzyme deactivation constant (k~d~) and their functional relationships to temperature were determined experimentally. The optimization problem was formulated in terms of maximization of fructose productivity as the objective function. The optimization problem was solved by making use of a maximum principle and the control vector iteration method. Approximately optimal temperature control policy was employed as compared with the reactor operation at an optimum constant temperature.

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