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Optimization of lentiviral vectors for the gene therapy of fanconi anemia

✍ Scribed by Africa Gonzalez-Murillo; M. Luz Lozano; Javier Molina-Estevez; Elena Almarza; Montserrat Aldea; Lara Alvarez; Guillermo Guenechea; Juan A. Bueren; Paula Rio


Book ID
116304512
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
54 KB
Volume
40
Category
Article
ISSN
1079-9796

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Gene transfer vectors based on retroviruses including oncogenic retroviruses and lentiviruses provide effective means for the delivery, integration and expression of exogenous genes in mammalian cells. Lentiviral (LV) vectors provide attractive gene delivery vehicles in the context of non-dividing c