Optimization of global DNA methylation measurement by LC-MS/MS and its application in lung cancer patients

Determination of cyclophosphamide enanti

Determination of cyclophosphamide enantiomers in plasma by LC-MS/MS: Application to pharmacokinetics in breast cancer and lupus nephritis patients

✍ Carolina De Miranda Silva; Bruno Jose Dumêt Fernandes; Maria Paula Marques Perei 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 170 KB

## Abstract This article describes the enantioselective analysis of cyclophosphamide (CPA) in human plasma using LC‐MS/MS. CPA enantiomers were extracted from plasma using a mixture of ethyl acetate and chloroform (75:25, v/v). The enantiomers were separated on a Chiralcel® OD‐R column, with the mo

Direct analysis of tobacco-specific nitr

Direct analysis of tobacco-specific nitrosamine NNK and its metabolite NNAL in human urine by LC–MS/MS: evidence of linkage to methylated DNA lesions

✍ Hu, Chiung-Wen; Hsu, Yu-Wen; Chen, Jian-Lian; Tam, Lai-Man; Chao, Mu-Rong 📂 Article 📅 2013 🏛 Springer-Verlag 🌐 English ⚖ 475 KB

Measurement of Total and Unbound Mycophe

Measurement of Total and Unbound Mycophenolic Acid and Its Glucuronide by LC Coupled with MS. Application to a Pharmacokinetic Study of Mycophenolate Mofetil in Patients with Autoimmune Diseases

✍ Sarah Djabarouti; Pierre Duffau; Fabien Xuereb; Estibaliz Lazaro; Carine Greib; 📂 Article 📅 2009 🏛 Springer 🌐 English ⚖ 387 KB

A Rapid, Reproducible, On-the-Fly Orthog

A Rapid, Reproducible, On-the-Fly Orthogonal Array Optimization Method for Targeted Protein Quantification by LC/MS and Its Application for Accurate and Sensitive Quantification of Carbonyl Reductases in Human Liver

✍ Cao, Jin; Covarrubias, Vanessa M.; Straubinger, Robert M.; Wang, Hao; Duan, Xiao 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 664 KB

A Rapid, Reproducible, On-the-Fly Orthog

A Rapid, Reproducible, On-the-Fly Orthogonal Array Optimization Method for Targeted Protein Quantification by LC/MS and Its Application for Accurate and Sensitive Quantification of Carbonyl Reductases in Human Liver

✍ Cao, Jin; Gonzalez-Covarrubias, Vanessa; Straubinger, Robert M.; Wang, Hao; Duan 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 21 KB