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Optimization of dose and dose regimen of biapenem based on pharmacokinetic and pharmacodynamic analysis

✍ Scribed by Toshihiko Takata; Kazumasa Aizawa; Atsuyuki Shimizu; Shiro Sakakibara; Hiroomi Watabe; Kyoichi Totsuka


Publisher
Springer
Year
2004
Tongue
English
Weight
441 KB
Volume
10
Category
Article
ISSN
1341-321X

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Pharmacokinetics and dosing regimen of a
✍ C. Belloli; G. Crescenzo; S. Carli; R. Villa; O. Sonzogni; G. Carelli; P. Ormas πŸ“‚ Article πŸ“… 1996 πŸ› Springer Netherlands 🌐 English βš– 513 KB

The kinetic behaviour of the aminoglycoside aminosidine, given at 15 mg/kg intravenously, intramuscularly and subcutaneously, was studied in 5 dogs to determine the appropriate dosage schedule. The pharmacokinetic behaviour of aminosidine in dogs was similar to that in other species, except that it