Optimization of the production of virus-
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Pedro E. Cruz; António Cunha; Cristina C. Peixoto; João Clemente; José L. Moreir
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Article
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1998
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John Wiley and Sons
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English
⚖ 345 KB
In this work the maximal operational hydrodynamic conditions (agitation and aeration rate) that cause no adverse effect in Sf-9 cells growth in SF900II serumfree medium were determined. Shear stresses higher than 1 N m -2 and aeration rates higher than 0.04 vvm affect cell growth and when these cond