Optimization of capillary electrophoresis method with contactless conductivity detection for the analysis of tobramycin and its related substances
β Scribed by Mohamed Nouri El-Attug; Jos Hoogmartens; Erwin Adams; Ann Van Schepdael
- Book ID
- 113743216
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 742 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0731-7085
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## Abstract CE with capacitively coupled contactless conductivity detection (C^4^D) was employed for the separation and detection of seven amphetamine analogues as well as amphetamine, dextroamphetamine, methamphetamine and 3,4βmethylenedioxymethamphetamine. The separation electrolyte was 30βmM hyd
One of the major drawbacks in the analysis of aminoglycoside antibiotics is their lack of UV chromophore and/or fluorophore. Tobramycin, a representative member of this group, was examined in this study. To overcome the detection hurdle, a precapillary derivatization followed by capillary electropho