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Optimization of basic parameters in temperature-programmed gas chromatographic separations of multi-component samples within a given time

✍ Scribed by D. Repka; J. Krupčik; A. Brunovská; P.A. Leclercq; J.A. Rijks


Book ID
104145700
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
448 KB
Volume
463
Category
Article
ISSN
1873-3778

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✦ Synopsis


A new procedure is introduced for the optimization of column peak capacity in a given time. The optimization focuses on temperature-programmed operating conditions, notably the initial temperature and hold time, and the programming rate. Based conceptually upon Lagrange functions, experiments were carried out along simplex sequential and central composite design procedures. The validity of the theory was demonstrated by separations of some crude oil distillation fractions.