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Optimization of a Liquid Chromatography−Tandem Mass Spectrometry Method for Quantification of the Plant Lignans Secoisolariciresinol, Matairesinol, Lariciresinol, and Pinoresinol in Foods

✍ Scribed by Milder, Ivon E. J.; Arts, Ilja C. W.; Venema, Dini P.; Lasaroms, Johan J. P.; Wähälä, Kristina; Hollman, Peter C. H.

Book ID
118221124
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
120 KB
Volume
52
Category
Article
ISSN
0021-8561

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## Abstract A sensitive high‐performance liquid chromatography–tandem mass spectrometry method was developed and validated for the quantification of quetiapine in rat plasma. Following liquid–liquid extraction, the analyte was separated using a gradient mobile phase on a reverse‐phase column and an