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Optimization and model reduction in the high dimensional parameter space of a budding yeast cell cycle model

✍ Scribed by Cihan Oguz, Teeraphan Laomettachit, Katherine C Chen, Layne T Watson…

Book ID
120684590
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
489 KB
Volume
7
Category
Article
ISSN
1752-0509

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## Abstract The Chen et al. (__Mol Biol Cell__ 2000, 11, 369–391) budding yeast cell cycle model is a biochemical kinetic model that describes how the controlling protein concentrations change during a proliferation cycle. Time dependence of local sensitivity coefficients was calculated for all var