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Optimisation of intraperitoneal cisplatin therapy with regional hyperthermia in rats

✍ Scribed by Los, Gerrit; Sminia, Peter; Wondergem, Jan; Mutsaers, Peter H.A.; Havemen, Jaap; ten Bokkel Huinink, Daan; Smals, Oskar; Gonzalez-Gonzalez, Dionisio; Gordon McVie, J.


Book ID
122973097
Publisher
Elsevier Science
Year
1991
Weight
872 KB
Volume
27
Category
Article
ISSN
0277-5379

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We have compared the therapeutic efficacy as well as the kinetics of treatment-induced apoptosis and necrosis of the maximum tolerated dose (MTD) of doxorubicin (DOX) or cisplatin (CDDP) combined with long-duration, low-temperature whole-body hyperthermia (LL-WBH, at 40.0Β°C for 6 hr), with the combi