Optimisation of containedNicotiana tabacumcultivation for the production of recombinant protein pharmaceuticals
β Scribed by Richard Colgan; Christopher J. Atkinson; Matthew Paul; Sally Hassan; Pascal M. W. Drake; Amy L. Sexton; Simon Santa-Cruz; David James; Keith Hamp; Colin Gutteridge; Julian K-C. Ma
- Book ID
- 106550573
- Publisher
- Springer Netherlands
- Year
- 2009
- Tongue
- English
- Weight
- 375 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0962-8819
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## Abstract Therapeutic proteins produced using recombinant DNA technologies are generally complex, heterogeneous, and subject to a variety of enzymatic or chemical modifications during expression, purification, and longβterm storage. The use of mass spectrometry (MS) for the evaluation of recombin