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Optimal versus maximally tolerated dose in cancer chemotherapy treatment

✍ Scribed by Maurie Markman


Book ID
112529646
Publisher
Springer-Verlag
Year
1993
Tongue
English
Weight
230 KB
Volume
119
Category
Article
ISSN
1432-1335

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Dosages of anticancer drugs are usually calculated on the basis of a uniform standard, the body surface area (BSA). Although many physiological functions are proportionate to BSA, overall drug clearance is only partially related to this parameter. Consequently, following administration of equivalent