𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Optimal Two-Stage Design for Case-Control Association Analysis Incorporating Genotyping Errors

✍ Scribed by Y. Zuo; G. Zou; J. Wang; H. Zhao; H. Liang

Book ID
111111412
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
163 KB
Volume
72
Category
Article
ISSN
0003-4800

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Optimal two-stage genotyping designs for
Optimal two-stage genotyping designs for genome-wide association scans
✍ Hansong Wang; Duncan C. Thomas; Itsik Pe'er; Daniel O. Stram 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 182 KB 👁 2 views

## Abstract The much‐anticipated fixed‐array, genome‐wide SNP genotyping technologies make large‐scale genome‐wide association scans now possible for large numbers of subjects. In this paper we reconsider the problem (Satagopan and Elston [2003] Genet Epidemiol 25:149–157) of optimizing a two‐stage

Linear trend tests for case–control gene
Linear trend tests for case–control genetic association that incorporate random phenotype and genotype misclassification error
✍ Derek Gordon; Chad Haynes; Yaning Yang; Patricia L. Kramer; Stephen J. Finch 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 267 KB

The purpose of this work is the development of linear trend tests that allow for error (LTT ae), specifically incorporating double-sampling information on phenotypes and/or genotypes. We use a likelihood framework. Misclassification errors are estimated via double sampling. Unbiased estimates of pen