In many randomized clinical trials with repeated measures of a response variable one anticipates a linear divergence over time in the difference between treatments. This paper explores how to make an efficient choice of analysis based on individual patient summary statistics. With the objective of e
โฆ LIBER โฆ
Optimal number of repeated measures and group sizes in clinical trials with linearly divergent treatment effects
โ Scribed by Bjorn Winkens; Hubert J.A. Schouten; Gerard J.P. van Breukelen; Martijn P.F. Berger
- Book ID
- 116350521
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 431 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1551-7144
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Linearly divergent treatment effects in
โ
Lars J. Frison; Stuart J. Pocock
๐
Article
๐
1997
๐
John Wiley and Sons
๐
English
โ 212 KB
๐ 2 views
Planning group sizes in clinical trials
โ
Hubert J. A. Schouten
๐
Article
๐
1999
๐
John Wiley and Sons
๐
English
โ 119 KB
๐ 2 views
Simple formulae have been derived for the accurate computation of sample sizes when the two-sample t-test is used. Required sample sizes may be reduced by taking repeated measures, especially if correlations are about equal. In a trial with two parallel groups, repeated measures may be summarized by
Intent-to-treat analysis of repeated mea
โ
B.M. Johnstone; R.L. Obenchain; E.T. Edgell; T.W Croghan; S.L. Tunis; T.J. Knies
๐
Article
๐
1998
๐
Elsevier Science
๐
English
โ 180 KB
A15 Planning clinical trials in OA: Rela
๐
Article
๐
2005
๐
Elsevier Science
๐
English
โ 101 KB
Effectiveness of lithium in subjects wit
โ
Cipriani, Andrea; Girlanda, Francesca; Agrimi, Emilia; Barichello, Andrea; Bened
๐
Article
๐
2013
๐
BioMed Central
๐
English
โ 184 KB
Clinical improvement as reflected in mea
โ
Peter Tugwell; George Wells; Vibeke Strand; Andreas Maetzel; Claire Bombardier;
๐
Article
๐
2000
๐
John Wiley and Sons
๐
English
โ 235 KB
๐ 2 views