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Optimal input design for identification of compartmental models. Theory and application to a model of glucose kinetics

✍ Scribed by Claudio Cobelli; Karl Thomaseth


Book ID
116029170
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
889 KB
Volume
77
Category
Article
ISSN
0025-5564

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A generalized nonlinear mathematical model which incorporates beta-cell kinetics, a glucose-insulin feedback system and a gastrointestinal absorption term for glucose, is presented. Numerical simulations using this model lead to time variations of plasma glucose and insulin levels that are consisten