## Abstract Design of experiment (DoE) is applied to establish the optimum ionization conditions for analyzing synthetic polymers via coupled size exclusion chromatography electrospray ionization mass spectrometry (SEC‐ESI‐MS) yielding maximum ionization efficiency. The ion source conditions were o
Optimal designs for testing the functional form of a regression via nonparametric estimation techniques
✍ Scribed by Stefanie Biedermann; Holger Dette
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 126 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0167-7152
No coin nor oath required. For personal study only.
✦ Synopsis
For the problem of checking linearity in a heteroscedastic nonparametric regression model under a ÿxed design assumption, we study maximin designs which maximize the minimum power of a nonparametric test over a broad class of alternatives from the assumed linear regression model. It is demonstrated that the optimal design depends sensitively on the used estimation technique (i.e. weighted or ordinary least-squares) and on an inner product used in the deÿnition of the class of alternatives. Our results extend and put recent ÿndings of Wiens (Statist. Probab. Lett. 12 (1991) 217) in a new light, who established the maximin optimality of the uniform design for lack-of-ÿt tests in homoscedastic multiple linear regression models.
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