Optimal design for nonlinear response mo
โ V V Fedorov; Sergei L Leonov
๐ Library
๐
2014
๐ CRC Press
๐ English
โฆ LIBER โฆ
๐
Optimal Design for Nonlinear Response Models
โ Scribed by Valerii V. Fedorov (Author); Sergei L. Leonov (Author)
- Publisher
- CRC Press
- Year
- 2013
- Leaves
- 398
- Edition
- 1
- Category
- Library
โฌ Acquire This Volume
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โฆ Synopsis
Optimal Design for Nonlinear Response Models discusses the theory and applications of model-based experimental design with a strong emphasis on biopharmaceutical studies. The book draws on the authors` many years of experience in academia and the pharmaceutical industry. While the focus is on nonlinear models, the book begins with an explanation of
โฆ Table of Contents
Regression Models and Their Analysis. Convex Design Theory. Algorithms and Numerical Techniques. Optimal Design under Constraints. Nonlinear Response Models. Locally Optimal Designs in Dose Finding. Examples of Optimal Designs in PK/PD Studies. Adaptive Model-Based Designs. Other Applications of Optimal Designs. Useful Matrix Formulae. Bibliography. Index.
โฆ Subjects
Bioscience;Biology;Statistics for the Biological Sciences;Pharmaceutical Science;Clinical Trials - Pharmaceutical Science;Mathematics & Statistics;Statistics & Probability;Statistics;Statistical Theory & Methods
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