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Optically active 1-Hydroxy-3-Methylbutanephosphonic Acid and its derivatives

โœ Scribed by Dr. M. Hoffmann


Book ID
105353670
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
274 KB
Volume
332
Category
Article
ISSN
1615-4150

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Procedures are reported for the conversion of 2,3-epoxysulfides to 3-hydroxy-1,2-dithioethers. Conventional nucleophih'c ring opening using a thiolate gives a mixture of products resulting from ring opening at C-2 and C-3, with the latter predominating. With sodium thiolates in DMF a competing [5-el