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Optical traps for single molecule biophysics: a primer

✍ Scribed by T.T. Perkins

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
575 KB
Volume
3
Category
Article
ISSN
1863-8880

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✦ Synopsis

Abstract

Optical trapping experiments of different complexities are making a significant impact in biology. This review seeks to highlight design choices for scientists entering the field or building new instruments and to discuss making calibrated measurements with optical traps. For specificity, this review focuses on nucleic acid‐based assays, but the discussion reflects the general experimental design considerations of developing a biological assay and an optical trap to measure it.

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