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Optical resolution of 1-alkyn-3-ol through the lipase-catalyzed enantioselective hydrolysis of the phenyl carbonate

✍ Scribed by Masatoshi Kawashima; Takashi Hasegawa


Publisher
Springer Netherlands
Year
1992
Tongue
English
Weight
112 KB
Volume
14
Category
Article
ISSN
0141-5492

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πŸ“œ SIMILAR VOLUMES


Lipase catalysed resolution of (R)- and
✍ Pietro Allevi; Pierangela Ciuffreda; Mario Anastasia πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 426 KB

Various (R)-and (S)-l-trimethylsilyl-l-alkyn-3-ols, chiral building units useful for the synthesis of biologically active compounds, have been efficiently resolved by enantioselective acetylation mediated by immobilized lipase PS. The resolution is applied to the synthesis of (R)-and (S)-5-octyl-2-(