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Optical, Redox, and DNA-Binding Properties of Phenanthridinium Chromophores: Elucidating the Role of the Phenyl Substituent for Fluorescence Enhancement of Ethidium in the Presence of DNA

✍ Scribed by Christa Prunkl; Markus Pichlmaier; Rainer Winter; Vladimir Kharlanov; Wolfgang Rettig; Hans-Achim Wagenknecht

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
497 KB
Volume
16
Category
Article
ISSN
0947-6539

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## Abstract The interaction of fluoroquinacrine, 3‐fluoro‐7‐chloro‐9‐(diethylamino‐1‐methylbutyl‐amino)acridine, with poly(A), DNA, and tRNA has been investigated by monitoring changes in the ^19^F‐nmr properties, the fluorescence, and the optical absorbance of the drug. The changes in the properti