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Optical properties of complexes of antimalarial drugs with ferriprotoporphyrin IX in aqueous medium: I. The system ferriprotoporphyrin IX-quinine

✍ Scribed by G. Blauer


Book ID
115706880
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
722 KB
Volume
251
Category
Article
ISSN
0003-9861

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Chloroquine (CQ) enantiomers were prepared by a novel synthesis starting from either (S)-or (R)-pyroglutamic acid. Light-absorption spectra of CQ and of complexes of ferriprotoporphyrin IX (FP) with CQ were measured in dilute aqueous solutions at pH 7.3 and 11.3. Spectrophotometric titrations at the