Optical Design for Biomedical Imaging (SPIE Press Monograph Vol. PM203)

✍ Scribed by Rongguang Liang

• Publisher: SPIE Press
• Year: 2011
• Tongue: English
• Leaves: 510
• Series: SPIE Press Monograph PM203
• Category: Library

✦ Synopsis

Designing an efficient imaging system for biomedical optics requires a solid understanding of the special requirements of the optical systems for biomedical imaging and the optical components used in the systems. However, a lack of reference books on optical design (imaging and illumination) for biomedical imaging has led to some inefficient systems. This book fills the gap between biomedical optics and optical design by addressing the fundamentals of biomedical optics and optical engineering, and biomedical imaging systems. The first half provides a brief introduction to biomedical optics and then covers the fundamentals of optics, optical components, light sources, detectors, optical imaging system design, and illumination system design. This also includes important issues related to biomedical imaging, such as autofluorescence from optical materials. The second half of the text covers various biomedical imaging techniques and their optical systems, along with design examples.

✦ Table of Contents

Contents......Page 6
Preface......Page 14
Acknowledgments......Page 15
List of Acronyms and Abbreviations......Page 16
1.1 Introduction......Page 19
1.2 Optical Signals in Biomedical Optical Imaging......Page 20
References......Page 30
2.1 Introduction to Optical Design......Page 31
2.2 Optical Properties......Page 36
2.3 Radiometry of Optical Systems......Page 39
2.4 Introduction to Aberrations......Page 43
2.5 Seidel Aberrations......Page 58
2.6 Performance Evaluations......Page 61
2.7 Correction of Aberrations......Page 69
2.8 Optical Design......Page 79
References......Page 83
3.1 Introduction......Page 85
3.2 Fundamentals of Optical Fibers......Page 86
3.3 Light Propagation in the Fiber......Page 90
3.4 Illumination Using Fiber Bundles......Page 102
3.5 Fiber-Optic Imaging Systems......Page 110
References......Page 118
4.1 Introduction......Page 121
4.2 Objective Lenses......Page 136
4.3 Tube Lens......Page 164
4.4 Eyepiece......Page 165
4.5 Illumination System......Page 170
References......Page 181
5.1 Introduction to Fluorescence......Page 183
5.2 Fluorescence Imaging Techniques......Page 189
5.3 Components in Fluorescence Imaging Systems......Page 191
5.4 Fluorescence Filters......Page 198
5.5 Fluorescence Imaging Systems......Page 214
5.6 Optical Designs of Fluorescence Imaging Systems......Page 235
References......Page 246
6.1 Basics of Polarized Light......Page 251
6.2 Polarized-Light Interactions with Tissues......Page 261
6.3 Polarization Imaging Systems in Biomedical Imaging......Page 264
6.4 Polarization Elements......Page 271
6.5 Polarization Effects in Optical Systems......Page 291
6.6 Optical Design and System Analysis......Page 310
References......Page 322
7.1 Introduction......Page 330
7.2 Basic Components and Requirements......Page 335
7.3 Confocal Scanning Systems......Page 346
7.4 Optical Design of the Objective Lens......Page 368
7.5 Fiber-Optic Confocal Imaging Systems......Page 376
References......Page 392
8.1 Introduction......Page 397
8.2 Basic Optics for Endoscopes......Page 398
8.3 Relay Lenses......Page 405
8.4 Objective Lenses......Page 416
8.5 Illumination Systems......Page 438
8.6 Wireless Endoscopes......Page 448
References......Page 460
Appendix: Lens Prescriptions......Page 463
Index......Page 501