๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Optical coherence tomography and Raman spectroscopy of the ex-vivo retina

โœ Scribed by Julia W. Evans; Robert J. Zawadzki; Rui Liu; James W. Chan; Stephen M. Lane; John S. Werner

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
589 KB
Volume
2
Category
Article
ISSN
1864-063X

No coin nor oath required. For personal study only.

โœฆ Synopsis

Abstract

Imaging the structure and correlating it with the biochemical content of the retina holds promise for fundamental research and for clinical applications. Optical coherence tomography (OCT) is commonly used to image the 3D structure of the retina and while the added functionality of biochemical analysis afforded by Raman scattering could provide critical molecular signatures for clinicians and researchers, there are many technical challenges to combine these imaging modalities. We describe an OCT microscope for exโ€vivo imaging combined with Raman spectroscopy capable of collecting morphological and molecular information about a sample simultaneously. We present our first results and discuss the challenges to further development of this dualโ€mode instrument and limitations for future inโ€vivo retinal imaging. (ยฉ 2009 WILEYโ€VCH Verlag GmbH & Co. KGaA, Weinheim)

๐Ÿ“œ SIMILAR VOLUMES

Ex vivo imaging of chronic total occlusi
Ex vivo imaging of chronic total occlusions using forward-looking optical coherence tomography
โœ Nigel R. Munce; Victor X.D. Yang; Beau A. Standish; Beiping Qiang; Jagdish Butan ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 471 KB ๐Ÿ‘ 1 views

## Abstract ## Background and Objectives Percutaneous coronary interventions (PCI) of chronic total occlusions (CTOs) of arteries are more challenging lesions to treat with angioplasty and stenting than stenotic vessels due primarily to the difficulty in guiding the wire across the lesion. Angiogr

In vivo optical coherence tomography for
In vivo optical coherence tomography for the diagnosis of oral malignancy
โœ Petra Wilder-Smith; Woong-Gyu Jung; Matthew Brenner; Kathryn Osann; Hamza Beydou ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 207 KB ๐Ÿ‘ 1 views

## Abstract ## Background and Objective Oral cancer results in 10,000 U.S. deaths annually. Improved highly sensitive diagnostics allowing early detection of oral cancer would benefit patient survival and quality of life. Objective was to investigate in vivo nonโ€invasive optical coherence tomograp