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Optic gliomas in children with neurofibromatosis type 1

โœ Scribed by A. M. Lund; F. Skovby


Book ID
105411716
Publisher
Springer
Year
1991
Tongue
English
Weight
398 KB
Volume
150
Category
Article
ISSN
0340-6997

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Optic pathway gliomas and brainstem gliomas are the predominant intracranial neoplasms associated with neurofibromatosis type 1 (NF1). Before the past 15 years, studies of optic pathway gliomas in NF1 were hampered by the inaccurate diagnosis of NF1, the unavailability of noninvasive neuroimaging te

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## Abstract Optic pathway glioma (OPG), seen in 15% to 20% of individuals with neurofibromatosis type 1 (NF1), account for significant morbidity in young children with NF1. Overwhelmingly a tumor of children younger than 7 years, OPG may present in individuals with NF1 at any age. Although many OPG