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Opposite effects of stress on dopamine release in the limbic system of drug-naive and chronically amphetamine-treated rats

โœ Scribed by Friedbert Weiss; Assunta Imperato; M.Antonietta Casu; M.Stefania Mascia; Gian Luigi Gessa


Book ID
119414116
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
63 KB
Volume
337
Category
Article
ISSN
0014-2999

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The effects of cocaine and d-amphetamine on extracellular glutamate and aspartate levels in the nucleus accumbens, prefrontal cortex, and striatum were studied by in vivo microdialysis in awake, freely moving rats. In the nucleus accumbens, glutamate levels were stimulated by cocaine (15-30 mg/kg, i