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Opposite effects of D-amphetamine on spontaneous neuronal activity in the neostriatum and nucleus accumbens

✍ Scribed by George V. Rebec; Kenneth S. Zimmerman


Book ID
118866185
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
408 KB
Volume
201
Category
Article
ISSN
0006-8993

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The effect of the D2-antagonist raclopride was investigated in two test situations, which are presumed to involve dopamine (DA) transmission within the nucleus accumbens of the rat. Local injection of d-amphetamine sulphate (10 gg/0.5 gl) produced a marked increase in motor activity, measured as mot