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Opposite alterations of DNA methyltransferase gene expression in endometrioid and serous endometrial cancers

✍ Scribed by Yuning Xiong; Sean C. Dowdy; Ailing Xue; Jiang Shujuan; Norman L. Eberhardt; Karl C. Podratz; Shi-Wen Jiang

Book ID
113959719
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
561 KB
Volume
96
Category
Article
ISSN
0090-8258

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## Abstract Epigenetic aberration is known to be important in human carcinogenesis. Promoter methylation status of __RAS__ effector related genes, __RASSF1A, RASSF2A, hDAB2IP__ (m2a and m2b regions) and __BLU__, was evaluated in 76 endometrial carcinomas and their non‐neoplastic endometrial tissue