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Opposing regulatory effects of protein kinase C on the cAMP cascade in human HL-60 promyelocytic leukemia cells

โœ Scribed by Suh Byung-Chang; Choi Se-Young; Chun Jang-Soo; Kim Kyong-Tai

Book ID
114016399
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
341 KB
Volume
353
Category
Article
ISSN
0014-2999

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Activation of protein kinase C prevents
Activation of protein kinase C prevents induction of apoptosis by geranylgeraniol in human leukemia HL60 cells
โœ Yutaka Masuda; Madoka Yoda; Hidekazu Ohizumi; Toshihiro Aiuchi; Masahiko Watabe; ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 263 KB ๐Ÿ‘ 2 views

In a previous study, we showed that geranylgeraniol (GGO) is a potent inducer of apoptosis in human leukemia cells, including HL60 promyelocytic leukemia cells. The present study describes the effects of activators of protein kinase C (PKC) on GGO-induced apoptosis in various lines of leukemia cells