𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Opposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3

✍ Scribed by Sam Collins; Michael A. Lutz; Paul E. Zarek; Robert A. Anders; Gilbert J. Kersh; Jonathan D. Powell

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
388 KB
Volume
38
Category
Article
ISSN
0014-2980

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

EGR1, EGR2, and EGR3 activate the expres
EGR1, EGR2, and EGR3 activate the expression of their coregulator NAB2 establishing a negative feedback loop in cells of neuroectodermal and epithelial origin
✍ Joerg Kumbrink; Kathrin H. Kirsch; Judith P. Johnson 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 366 KB

## Abstract The inducible zinc finger transcription factors EGR1, EGR2, and EGR3 regulate the expression of numerous genes involved in differentiation, growth, and response to extracellular signals. Their activity is modulated in part through NAB2 which is induced by the same stimuli. In melanoma a

FasL promoter activation by IL-2 through
FasL promoter activation by IL-2 through SP1 and NFAT but not Egr-2 and Egr-3
✍ Sheng Xiao; Ken Matsui; Alan Fine; Bangmin Zhu; Ann Marshak-Rothstein; Russel L. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB

Recently activated peripheral T cells treated with IL-2 for 4 days expressed Fas ligand (FasL)-mediated cytotoxicity. These IL-2-treated T cells had high nuclear expression of SP1 and NFAT, but lacked the Egr-2 and Egr-3 that could be induced by anti-CD3 stimulation and had been implicated in FasL g

Specificity of transcriptional regulatio
Specificity of transcriptional regulation by the zinc finger transcription factors Sp1, Sp3, and Egr-1
✍ Alia Al-Sarraj; Regina M. Day; Gerald Thiel 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 246 KB

## Abstract The transcription factors Sp1, Sp3, and Egr‐1 bind with their zinc finger DNA‐binding domains to GC‐rich sequences in the regulatory regions of their target genes. The similarity of the DNA‐binding sites of Sp1, Sp3, and Egr‐1 has triggered the hypothesis that they compete for the same

Induction of Id-1 by FGF-2 involves acti
Induction of Id-1 by FGF-2 involves activity of EGR-1 and sensitizes neuroblastoma cells to cell death
✍ Giovanni Passiatore; Antonio Gentilella; Slava Rom; Marco Pacifici; Valeria Berg 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 470 KB

Inhibitor of differentiation-1 (Id-1) is a member of helix-loop-helix (HLH) family of proteins that regulate gene transcription through their inhibitory binding to basic-HLH transcription factors. Similarly to other members of this family, Id-1 is involved in the repression of cell differentiation a

Signaling pathways mediating induction o
Signaling pathways mediating induction of the early response genes prostaglandin G/H synthase-2 and egr-1 by serotonin via 5-HT2A receptors
✍ Margarete Goppelt-Struebe; Martin Stroebel 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 202 KB 👁 1 views

Signaling pathways responsible for serotonin (5-HT)-mediated induction of early response genes prostaglandin G/H synthase-2 (PGHS-2, cyclooxygenase-2) and egr-1 were investigated in rat mesangial cells. Gene induction by 5-HT was dependent on 5-HT 2A receptors that were pertussis toxin insensitive i