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Opposing Effects of Protein Kinase C δ and Protein Kinase B α on H2O2-Induced Apoptosis in CHO Cells

✍ Scribed by Hiroaki Konishi; Hidenori Matsuzaki; Hiroshi Takaishi; Toshiyoshi Yamamoto; Mizuho Fukunaga; Yoshitaka Ono; Ushio Kikkawa


Book ID
115584675
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
256 KB
Volume
264
Category
Article
ISSN
0006-291X

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## Abstract This report describes that protein kinase C delta (PKCδ) overexpression prevents TRAIL‐induced apoptosis in breast tumor cells; however, the regulatory mechanism(s) involved in this phenomenon is(are) incompletely understood. In this study, we have shown that TRAIL‐induced apoptosis was