Opposing Changes in Osteocalcin Levels in Bone vs Serum During the Acquisition of Peak Bone Density in C3H/HeJ and C57BL/6J Mice
β Scribed by X. Li; A.K. Srivastava; W. Gu; G. Masinde; S. Mohan; D.J. Baylink
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 141 KB
- Volume
- 71
- Category
- Article
- ISSN
- 1432-0827
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## Abstract C3H/HeJ(C3H) mice are approximately 50βfold more susceptible to liverβtumor induction than C57BL/6J(B6) mice. This difference in susceptibility is a consequence of allelic differences in hepatocarcinogen sensitivity(__Hcs__) genes that control the growth of preneoplastic lesions in the
To assess genetic factors determining sensitivity to streptozotocin-induced diabetes in inbred strains of mice, a genetic analysis of streptozotocin-sensitive C57BL/6J and streptozotocin-resistant C3H/HeJ mice was performed. One week after a single dose of streptozotocin (200 mg/kg body weight), dif