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Opposing cardiac effects of autoantibody activation of beta-adrenergic and M2 muscarinic receptors in cardiac-related diseases

✍ Scribed by Stavros Stavrakis; David C. Kem; Eugene Patterson; Pedro Lozano; Shijun Huang; Bela Szabo; Madeleine W. Cunningham; Ralph Lazzara; Xichun Yu


Book ID
116549052
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
493 KB
Volume
148
Category
Article
ISSN
0167-5273

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Tricyclohexyltin hydroxide effects on ca
✍ Sahib, Kabeer I. Ahammad ;Desaiah, Durisala πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 633 KB

Previous studies from this laboratory have indicated that tricyclohexyltin hydroxide (Plictran) is a potent inhibitor of both basal-and isoproterenol-stimulated cardiac sarcoplasmic reticulum (SR) Ca2+-ATPase, with an estimated IC-50 of 2.5 x 1W8M. The present studies were initiated to evaluate the